Monographs

In collaboration with NMS Labs, medical examiner and coroner offices, crime laboratories, clinical partners, and the National Institute of Justice (NIJ), the CFSRE is documenting the first reports of NPS in the United States through analysis of seized materials and/or biological fluids. These reports are generated using comprehensive analytical techniques (e.g. GC-MS, LC-QTOF-MS, NMR) and include available information about the new substances identified at the time of reporting, as well as the analytical data generated during testing.These reports are intended to assist with the rapid identification of NPS in forensic casework and related disciplines, and should not be used for confirmatory purposes alone.

The data in our new drug monographs are not externally peer-reviewed, however, the data are reviewed and interpreted internally by our leading scientific staff. All identifications are required to meet minimum criteria during review (e.g. mass error <5 ppm, retention within 0.05 minutes for GC-MS or 0.35 minutes for LC-QTOF-MS, expected vs. acquired fragmentation pattern match, etc.), depending on the analyses performed and the availability of a standard reference material. Contact our program for more information about our review and reporting processes.




Date Class Compound Structure Formula MW [M+] [M+H]+
07/21/2022 Stimulant N-Propyl Butylone C14H19NO3 249.3 249 250.1438 Download PDF
06/21/2022 Cannabinoid CH-FUBIATA C23H25FN2O 364.5 364 365.2024 Download PDF
06/09/2022 Stimulant N-Cyclohexyl Butylone C17H23NO3 289.4 289 290.1751 Download PDF
05/26/2022 Cannabinoid ADB-5’Br-BINACA C18H25BrN4O2 409.3 408 409.1234 Download PDF
05/19/2022 Cannabinoid BZO-4en-POXIZID C20H19N3O2 333.4 333 334.1550 Download PDF
05/17/2022 Cannabinoid ADB-5Br-INACA C14H17BrN4O2 353.2 352 353.0608 Download PDF
05/17/2022 Cannabinoid MDMB-5Br-INACA C15H18BrN3O3 368.2 367 368.0604 Download PDF
05/09/2022 Stimulant N-Cyclohexyl Methylone C16H21NO3 275.3 275 276.1594 Download PDF
04/29/2022 Cannabinoid CH-PIATA C21H30N2O 326.5 326 327.2431 Download PDF
03/14/2022 Opioid Dipyanone C23H29NO 335.5 335 336.2322 Download PDF
12/20/2021 Cannabinoid EDMB-PINACA C21H31N3O3 373.5 373 374.2438 Download PDF
12/17/2021 Stimulant N,N-Dimethylpentylone C14H19NO3 249.3 249 250.1438 Download PDF
12/16/2021 Opioid Napthyl-U-47700 C20H26N2O 310.4 310 311.2118 Download PDF
12/15/2021 Hallucinogen Tenocyclidine C15H23NS 249.4 249 250.1624 Download PDF
12/14/2021 Opioid Trifluoromethyl-U-47700 C17H23F3N2O 328.4 328 329.1835 Download PDF
11/22/2021 Opioid N-Piperidinyl Etonitazene C23H28N4O3 408.5 408 409.2234 Download PDF
11/19/2021 Cannabinoid ADB-PHETINACA C22H26N4O2 378.5 378 379.2129 Download PDF
11/18/2021 Cannabinoid BZO-CHMOXIZID C22H23N3O2 361.4 361 362.1863 Download PDF
11/17/2021 Cannabinoid ADB-FUBIATA C23H26FN3O2 395.5 395 396.2082 Download PDF
11/05/2021 Benzodiazepine Fluclotizolam C15H10ClFN4S 332.8 332 333.0372 Download PDF
10/19/2021 Cannabinoid 5F-BZO-POXIZID C20H20FN3O2 353.4 353 354.1612 Download PDF
10/19/2021 Cannabinoid BZO-HEXOXIZID C21H23N3O2 349.4 349 350.1863 Download PDF
10/19/2021 Cannabinoid BZO-POXIZID C20H21N3O2 335.4 335 336.1707 Download PDF
09/22/2021 Opioid Metodesnitazene C21H27N3O 337.5 337 338.2227 Download PDF
06/29/2021 Hallucinogen 4-AcO-EPT C17H24N2O2 288.4 288 289.1911 Download PDF
05/26/2021 Opioid Protonitazene C23H30N4O3 410.5 410 411.2391 Download PDF
05/13/2021 Opioid N-Pyrrolidino Etonitazene C22H26N4O3 394.5 394 395.2078 Download PDF
04/29/2021 Cannabinoid ADB-HEXINACA C20H30N4O2 358.5 358 359.2442 Download PDF
04/23/2021 Stimulant Methylenedioxy-PV8 C18H25NO3 303.4 303 304.1907 Download PDF
03/26/2021 Opioid Flunitazene C20H23FN4O2 370.4 370 371.1878 Download PDF
03/04/2021 Cannabinoid ADB-4en-PINACA C19H26N4O2 342.4 342 343.2129 Download PDF
02/23/2021 Opioid Etodesnitazene C22H29N3O 351.5 351 352.2383 Download PDF
02/16/2021 Benzodiazepine Deschloroetizolam C17H16N4S 308.4 308 309.1168 Download PDF
02/04/2021 Hallucinogen Cl-PCP C17H24ClN 277.8 277 278.1670 Download PDF
02/04/2021 Hallucinogen F-PCP C17H24FN 261.4 261 262.1966 Download PDF
01/27/2021 Cannabinoid 4F-ABINACA C22H28FN3O 369.5 369 370.2289 Download PDF
01/15/2021 Opioid Butonitazene C24H32N4O3 424.5 424 425.2547 Download PDF
12/17/2020 Opioid Bromofentanyl C22H27BrN2O 415.4 414 415.1380 Download PDF
12/17/2020 Opioid Chlorofentanyl C22H27ClN2O 370.9 370 371.1885 Download PDF
12/17/2020 Opioid Fluorofentanyl C22H27FN2O 354.5 354 355.2180 Download PDF
12/10/2020 Hallucinogen MeO-PCE C15H23NO 233.4 233 234.1852 Download PDF
12/03/2020 Cannabinoid 5F-EDMB-PICA C22H31FN2O3 390.5 390 391.2391 Download PDF
12/01/2020 Stimulant 4-Fluoro-3-Methyl-Alpha-PVP C16H22FNO 263.4 263 264.1758 Download PDF
11/18/2020 Cannabinoid ADB-BINACA C18H26N4O2 330.4 330 331.2129 Download PDF
11/11/2020 Opioid AP-238 C18H26N2O 286.4 286 287.2118 Download PDF
08/11/2020 Benzodiazepine Adinazolam C19H18ClN5 351.8 351 352.1323 Download PDF
07/30/2020 Opioid Metonitazene C21H26N4O3 382.5 382 383.2078 Download PDF
07/17/2020 Opioid Brorphine C20H22BrN3O 400.3 399 400.1019 Download PDF
07/06/2020 Benzodiazepine Metizolam C16H13ClN4S 328.8 328 329.0622 Download PDF
07/01/2020 Cannabinoid 4F-MDMB-BICA C20H27FN2O3 362.4 362 363.2078 Download PDF
06/15/2020 Cannabinoid 5F-EMB-PICA C21H29FN2O3 376.5 376 377.2235 Download PDF
06/09/2020 Stimulant Hexylone C14H19NO3 249.3 249 250.1438 Download PDF
05/29/2020 Cannabinoid 5F-CUMYL-PINACA C22H26FN3O 367.5 367 368.2133 Download PDF
05/27/2020 Stimulant alpha-PCYP C18H25NO 271.4 271 272.2009 Download PDF
05/07/2020 Stimulant 4F-Ethylphenidate C15H20FNO2 265.3 265 266.1551 Download PDF
05/01/2020 Benzodiazepine Bromazolam C17H13BrN4 353.2 352 353.0396 Download PDF
04/13/2020 Stimulant Methoxpropamine (MXPr) C16H23NO2 261.4 261 262.1802 Download PDF
04/13/2020 Opioid para-Methyl AP-237 C18H26N2O 286.4 286 287.2118 Download PDF
03/24/2020 Opioid N-Ethyl-U-47700 C17H24Cl2N2O 343.3 342 343.1338 Download PDF
03/11/2020 Opioid 3,4-Difluoro-U-47700 C16H22F2N2O 296.4 296 297.1773 Download PDF
02/24/2020 Stimulant N-Ethyl Pentedrone C13H19NO 205.3 205 206.1539 Download PDF
12/12/2019 Hallucinogen 3-HO-PCE C14H21NO 219.3 219 220.1696 Download PDF
12/03/2019 Stimulant 4F-Pentedrone C12H16FNO 209.3 209 210.1289 Download PDF
11/26/2019 Opioid para-Methylcyclopropylfentanyl C24H30N2O 362.5 362 363.2431 Download PDF
11/22/2019 Opioid N-Methyl U-47931E C16H23BrN2O 339.3 338 339.1067 Download PDF
11/19/2019 Opioid Isotonitazene C23H30N4O3 410.5 410 411.2391 Download PDF
11/15/2019 Opioid 2F-Viminol C21H31FN2O 346.5 346 347.2493 Download PDF
10/31/2019 Stimulant 3,4-Dichloromethylphenidate C14H17Cl2NO2 302.2 301 302.0709 Download PDF
10/31/2019 Stimulant Isopropylphenidate C16H23NO2 261.4 261 262.1802 Download PDF
10/11/2019 Cannabinoid MMB-4en-PICA C20H26N2O3 342.4 342 343.2016 Download PDF
09/30/2019 Stimulant N-ethyl Heptedrone C15H23NO 233.4 233 234.1852 Download PDF
09/18/2019 Opioid Piperidylthiambutene C17H21NS2 303.5 303 304.1188 Download PDF
09/16/2019 Opioid AP-237 C17H24N2O 272.4 272 273.1961 Download PDF
09/12/2019 Cannabinoid MDMB-4en-PINACA C20H27N3O3 357.5 357 358.2125 Download PDF
07/03/2019 Stimulant N-butyl Hexedrone C16H25NO 247.4 247 248.2009 Download PDF
06/25/2019 Benzodiazepine Flualprazolam C17H12ClFN4 326.8 326 327.0807 Download PDF
06/21/2019 Opioid 2-Methyl AP-237 C18H26N2O 286.4 286 287.2118 Download PDF
06/18/2019 Miscellaneous Furanyl UF-17 C19H24N2O2 312.4 312 313.1910 Download PDF
06/18/2019 Miscellaneous UF-17 C17H26N2O 274.4 274 275.2118 Download PDF
06/04/2019 Stimulant Benzylone (BMDP) C17H17NO3 283.3 283 284.1281 Download PDF
05/29/2019 Hallucinogen 4-HO-MET C13H18N2O 218.3 218 219.1492 Download PDF
05/16/2019 Stimulant N-butyl Pentylone C16H23NO3 277.4 277 278.1751 Download PDF
04/30/2019 Opioid 2’,5’-Dimethoxyfentanyl C24H32N2O3 396.5 396 397.2486 Download PDF
04/23/2019 Opioid para-Methoxyfuranylfentanyl C25H28N2O3 404.5 404 405.2173 Download PDF
04/16/2019 Hallucinogen 1P-LSD C23H29N3O2 379.5 379 380.2333 Download PDF
03/18/2019 Stimulant N,N-Diethyl Hexedrone C16H25NO 247.4 247 248.2009 Download PDF
03/11/2019 Hallucinogen 25C-NBOH C17H20ClNO3 321.8 321 322.1204 Download PDF
03/06/2019 Cannabinoid APP-BINACA C21H24N4O2 364.4 364 365.1972 Download PDF
02/12/2019 Cannabinoid 5F-MPP-PICA C24H27FN2O3 410.5 410 411.2078 Download PDF
02/04/2019 Hallucinogen 4-Acetoxy-MALT C16H20N2O2 272.3 272 273.1598 Download PDF
01/23/2019 Opioid Fluorofuranylfentanyl C24H25FN2O2 392.5 392 393.1973 Download PDF
01/11/2019 Cannabinoid 4F-MDMB-BINACA C19H26FN3O3 363.4 363 364.2031 Download PDF
01/03/2019 Stimulant 4-Fluoroethamphetamine C11H16FN 181.3 181 182.1340 Download PDF
12/19/2018 Benzodiazepine Nitrazolam C17H13N5O2 319.3 319 320.1142 Download PDF
10/30/2018 Stimulant 4-CDMC C11H14ClNO 211.7 211 212.0837 Download PDF
10/30/2018 Stimulant alpha-PiHP C16H23NO 245.4 245 246.1852 Download PDF
10/30/2018 Opioid U-47931E C15H21BrN2O 325.2 324 325.0910 Download PDF
10/18/2018 Cannabinoid MFUBINAC C16H13FN2O2 284.3 284 285.1034 Download PDF
10/05/2018 Cannabinoid 5Cl-AB-PINACA C18H25ClN4O2 364.9 364 365.1739 Download PDF
10/05/2018 Cannabinoid 5F-AB-PFUPPYCA C20H26F2N4O2 392.4 392 393.2097 Download PDF
10/05/2018 Opioid Precursor Despropionyl para-Fluorobenzylfentanyl C18H21FN2 284.4 284 285.1762 Download PDF
10/05/2018 Opioid Precursor para-Fluorocyclopropylbenzylfentanyl C22H25FN2O 352.4 352 353.2024 Download PDF
09/04/2018 Hallucinogen 2F-Deschloroketamine C13H16FNO 221.3 221 222.1289 Download PDF
09/04/2018 Stimulant 3,4-Methylenedioxy-alpha-PHP C17H23NO3 289.4 289 290.1751 Download PDF
09/04/2018 Stimulant Eutylone C13H17NO3 235.3 235 236.1281 Download PDF
09/04/2018 Opioid Phenylfentanyl C26H28N2O 384.5 384 385.2274 Download PDF
08/06/2018 Stimulant Tertylone C14H19NO3 249.3 249 250.1438 Download PDF
07/31/2018 Cannabinoid 5F-MDMB-PICA C21H29FN2O3 376.5 376 377.2235 Download PDF
06/01/2018 Hallucinogen Deschloro-N-ethyl Ketamine C14H19NO 217.3 217 218.1539 Download PDF
05/18/2018 Opioid Isopropyl-U-47700 C18H26Cl2N2O 357.3 356 357.1495 Download PDF
05/18/2018 Opioid Methylenedioxy-U-47700 C17H24N2O3 304.4 304 305.1860 Download PDF
05/04/2018 Stimulant 3,4-Dichloroethcathinone (DCEC) C11H13Cl2NO 246.1 245 246.0447 Download PDF
04/27/2018 Opioid Precursor Benzylfuranylfentanyl C23H24N2O2 360.5 360 361.1911 Download PDF
04/19/2018 Stimulant N-ethyl Hexylone C15H21NO3 263.3 263 264.1594 Download PDF
04/10/2018 Cannabinoid 5Br-AKB48 C23H30BrN3O 444.4 443 444.1645 Download PDF
04/10/2018 Cannabinoid 5Cl-AKB48 C23H30ClN3O 400.0 399 400.2150 Download PDF
04/10/2018 Cannabinoid 5F-EDMB-PINACA C21H30FN3O3 391.5 391 392.2344 Download PDF
04/10/2018 Opioid Precursor N-methyl Norfentanyl C15H22N2O 246.4 246 247.1805 Download PDF
03/27/2018 Opioid Precursor Despropionyl 3-Methylfentanyl C20H26N2 294.4 294 295.2169 Download PDF
03/27/2018 Opioid Precursor Despropionyl ortho-Methylfentanyl C20H26N2 294.4 294 295.2169 Download PDF
03/27/2018 Opioid ortho-Methylmethoxyacetylfentanyl C23H30N2O2 366.5 366 367.2380 Download PDF
03/26/2018 Opioid U-48800 C17H24Cl2N2O 343.3 342 343.1338 Download PDF
03/20/2018 Cannabinoid Adamantyl-CHMINACA C25H33N3O 391.6 391 392.2696 Download PDF
02/27/2018 Hallucinogen 25E-NBOH C19H25NO3 315.4 315 316.1907 Download PDF
02/27/2018 Stimulant 4-MDEC C14H21NO 219.3 219 220.1696 Download PDF
02/27/2018 Hallucinogen N-Acetyl 25I-NBOMe C20H24INO4 469.3 469 470.0823 Download PDF