2C-B-FLY

The following information was compiled in June 2025 and is subject to change as new research is conducted and as new information becomes available:

Description: 2C-B-FLY is a novel hallucinogen. Its structure bares a phenethylamine core and it resembles other substituted phenethylamines (e.g., 2C-B). 2C-B-FLY was first identified by our laboratory in February 2025 and confirmed after acquiring standard reference material.

Sample Source: San Francisco Aids Foundation (San Francisco, CA)

Sample Appearance: Solid green material

Pharmacology: 2C-B-FLY is a partial agonist at the serotonin 5-HT_2A receptor similar to 2C-B, and also has high affinity for the 5-HT_2B, 5-HT_2C, and 5-HT_2D receptors.^1,2

Toxicology: 2C-B-FLY has not been detected in toxicology cases to date at the CFSRE.

Drug Materials: 2C-B-FLY has been detected in one drug material to date at the CFSRE.

Demographics / Geographics: The drug material originated from California. 2C-B-FLY was identified alongside PCP.

Legal Status: 2C-B-FLY is not currently scheduled in the United States.

Class:

Hallucinogen

Appearance:

Solid green material

Formula:

C12H14BrNO2

MW:

284.1

[M+]:

283

[M+H]+:

284.0281

IUPAC:

2-(4-bromo-2,3,6,7-tetrahydrofuro[2,3-f]benzofuran-8-yl)ethanamine

Report Date:

June 26, 2025