The CFSRE is developing quarterly trend reports associated with NPS occurrence in the United States. These trend reports are intended to provide near real-time information regarding NPS prevalence, positivity, and turnover. Testing was performed using biological fluids, sample extracts, and/or datafiles. The CFSRE received funding from the National Institute of Justice (NIJ) of the Department of Justice (DOJ) to develop this initiative. For more information regarding our trend reports, please contact us at This email address is being protected from spambots. You need JavaScript enabled to view it..

Trend Reports are available for:


The Year in Review—2021

Since 2018, NPS Discovery has reported 116 newly discovered NPS in the United States (Figure 1). NPS opioids remain the largest subclass (Figure 2). In 2021, NPS Discovery reported the discovery of 27 NPS for the first time.

New NPS Reported 2018 to 2021 Bar GraphFigure 1: Newly discovered NPS reported for the first time, since 2018.
New NPS Reported 2018 to 2021 DoughnutFigure 2: Breakdown, by subclass, of newly discovered NPS, 2018-2021.
 
Since 2018, NPS Discovery has identified 197 NPS in forensic samples (Figure 3). NPS opioids, stimulants, and cannabinoids represent the largest subclasses observed. In 2021, 97 total NPS were detected (Figure 4).

NPS Identified Each Year by NPS Discovey since 2018 Pie ChartFigure 3: Breakdown, by subclass, of individual NPS detected 2018-2021
NPS Identified Each Year by NPS Discovey since 2018 Bar GraphFigure 4: Individual NPS detected each year, cumulative since 2018.
 
In 2021, NPS Discovery observed more than 2700 total NPS detections within examined sample populations (Figure 5), a portion of more than 8100 total NPS detections since our program launched in 2018 (Figure 6).

Total NPS Detected Each Year by NPS Discovey since 2018 Bar Graph Figure 5: Total number of NPS detections among all samples analyzed since 2018.
Total NPS Detected Each Year by NPS Discovey since 2018 Area GraphFigure 6: Cumulative number of NPS detections since 2018.
 
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