Dicloqualone

The following information was compiled in June 2025 and is subject to change as new research is conducted and as new information becomes available:

Description: Dicloqualone is categorized as a quinazolinone and bears structural similarity to other “quaaludes” such as methaqualone. Dicloqualone was first identified in California in early 2022 and has subsequently been identified across the United States.^1,2,3 Dicloqualone was identified by our laboratory in November 2024 and confirmed after acquiring standard reference material.

Sample Source: Chicago Recovery Alliance (Chicago, IL)

Sample Appearance: White powder

Pharmacology: Dicloqualone has sedative properties and increases the activity of GABA receptors similar to that of methaqualone.^4,5

Toxicology: Dicloqualone has not been detected in toxicology cases to date at the CFSRE.

Drug Materials: Dicloqualone has been detected in one drug material to date at the CFSRE.

Demographics / Geographics: The drug material originated from Chicago, IL, and dicloqualone was found alongside opioids (e.g., fentanyl, heroin) and diphenhydramine.

Legal Status: Dicloqualone is not currently scheduled in the United States.

Class:

Miscellaneous

Appearance:

White powder

Formula:

C16H12Cl2N2O

MW:

319.2

[M+]:

318

[M+H]+:

319.0399

IUPAC:

5-chloro-3-(4-chloro-2-methyl-phenyl)-2-methyl-quinazolin-4-one

Report Date:

June 17, 2025