Andrew Miller, Alex Krotulski, Sara Walton, Anna Dulaney, Aaron Frolichstein, Haley Dusek, Christine Murphy
JACC Case ReportsAbstract
Kratom is derived from Mitragyna speciosa and contains active alkaloids that bind opioid, alpha-2 adrenergic, and 5-HT2A receptors. In vitro studies show kratom can inhibit myocardial potassium channels. We present a patient who developed a reversible Brugada pattern and QT prolongation after self-treating his attention-deficit/hyperactivity disorder with kratom.
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