January 13, 2022

High-throughout Seminal Fluid Identification by Automated Immunoaffinity Mass Spectrometry

Under an award from the Department of Defense, scientists at the CFSRE have recently published a research article in The Journal of Forensic Sciences focusing streamlining the identification of seminal fluid in sexual assault evidence. This work improved upon traditional protein mass spectrometry techniques by coupling automated affinity purification with high-throughput targeted mass spectrometry.
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January 7, 2022

How Philadelphia Gets Ahead Of Drug Trends

Drug checking is a harm reduction strategy aimed at better understanding drug supplies and alerting people who use drugs about the dangers associated. Drug checking is increasingly being employed by public health agencies across the United States. The CFSRE and the Philadelphia Department of Public Health have developed a collaborative drug checking initiative. 
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December 29, 2021

A New Algorithm Could Help Prevent Drug Overdoses

Since the introduction of novel psychoactive substances (NPS) into the recreational drug supply more than a decade ago, public health and safety official have continued to ask “what drugs are next?” There have been many research initiatives aimed at tackling this question, including a new computer science algorithm – DarkNPS. While the program sound promising, not all scientists are convinced of its utility. CFSRE Associate Director Dr. Alex Krotulski was quoted saying “In a practical sense, nobody ever knows what’s coming next.”
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November 12, 2021

New Opioids - Ten Times the Strength of Fentanyl - Create Battleground for US Medics

As the opioid epidemic continues in the United States, new synthetic opioids have emerged with alarming increased potency. Fentanyl remains the primary synthetic opioid identified in forensic casework, however, a new second tier of opioids has emerged – the “nitazenes”. According to ongoing research studies, nitazenes can be "way more potent than fentanyl, which is really scary," said CFSRE Associate Director Dr. Alex Krotulski.
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June 1, 2021

NPS Discovery and the Hunt for New Drugs of Abuse

The National Institute of Justice (NIJ) under the Department of Justice (DOJ) has funded various research initiatives are the CFSRE, including grant opportunities that have helped facilitate the development of novel toxicology workflows and methodologies that are now used extensively by our NPS Discovery program. NIJ continues to support NPS Discovery and its hunt for new drugs of abuse in forensic toxicology and crime lab samples.
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