Since 2018, NPS Discovery has reported 154 newly discovered NPS in the United States (Figure 1). NPS opioids remain the largest subclass (Figure 2). In 2023, NPS Discovery reported the discovery of 17 NPS for the first time.

Figure 1Figure 1: Newly discovered NPS reported for the first time since 2018.
Figure 2Figure 2: Breakdown by subclass of newly discovered NPS, 2018-2023.
 

Since 2018, NPS Discovery has identified 240 NPS in forensic samples (Figure 3). NPS opioids, stimulants, and cannabinoids represent the largest subclasses observed. In 2023, 79 total NPS were detected (Figure 4).

Figure 3Figure 3: Breakdown by subclass of individual NPS detected 2018-2023
Figure 4Figure 4: Individual NPS detected each year, cumulative since 2018.
 

In 2023, NPS Discovery observed more than 3,600 total NPS detections within examined sample populations (Figure 5), a portion of more than 15,000 total NPS detections since our program launched in 2018 (Figure 6).

Figure 5 Figure 5: Total number of NPS detections by year among samples analyzed since 2018.
Figure 6Figure 6: Cumulative number of total NPS detections since 2018.
 
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