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Toxic Adulterants Found in Umbilical Cord Tissue (UCT)
In utero drug exposure is a significant public health threat to the well-being and normal development of the neonate. Recently, testing of umbilical cord tissue (UCT) has been employed to measure illicit drug exposure. UCT testing is a well-established...
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Analysis of Umbilical Cord Tissue as an Indicator of In Utero Exposure to Toxic Adulterating Substances
Midthun KM, Nelson BN, Strathmann FG, Browne T, Logan BK Frontiers in Pediatrics Abstract In utero drug exposure is a significant public health threat to the well-being and normal development of the neonate. Recently, testing of umbilical cord tissue...
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Identification of a Novel Opioid, N-piperidinyl Etonitazene (Etonitazepipne), in Patients with Suspected Opioid Overdose
Calello DP, Aldy K, Jefri M, Nguyen TAT, Krotulski AJ, Logan BK, Brent J, Wax P, Walton SW, Manini AF, on Behalf of the ToxIC Fentalog Study Group Clinical Toxicology Background Novel opioids in the illicit drug supply, such as the “nitazene” group of...
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Drug-Impaired Driving: The Contribution of Emerging and Undertested Drugs
Impaired driving is often associated with alcohol use and frequently leads to accidents, injuries, and fatalities. According to the National Highway Traffic Safety Administration, one person was killed every 39 minutes in an alcohol-related crash in...
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Identifying the Local Emergence of Medetomidine Through Prehospital Collaborations
Brian Rettger, Brittany P. Chapman, Alex J. Krotulski, Roland Gigliotti, Jyothi Polackal, Deborah Olabisi, John Nguyen, Brian Cotoni, Roland C Merchant, Sara Walton, Barry K. Logan, Patricia M. Martinez, Stacy Weisberg, John P. Broach, Kavita M. Babu...
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Plasma Pharmacokinetics and Pharmacodynamic Effects on the 2-Benzylbenzimidazole Synthetic Opioid, Isotonitazene, in Male Rats
Walton SE, Krotulski AJ, Glatfelter GC, Walther D, Logan BK, Baumann MH Psychopharmacology Rationale: Isotonitazene is an illicit synthetic opioid associated with many intoxications and fatalities. Recent studies show that isotonitazene is a potent...
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Medetomidine Quantitation and Enantiomer Differentiation in Biological Specimens Collected After Fatal and Non-Fatal Opioid Overdoses
Sara E Walton, Brianna N Stang, Sherri Kacinko, Donna M Papsun, Barry K Logan, Alex J Krotulski Journal of Analytical Toxicology Abstract Medetomidine is an alpha-2 agonist and non-opioid sedative. Its presence in illicit fentanyl and heroin drug...
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Identification of Synthetic Cathinones in Seized Materials: A Review of Analytical Strategies Applied in Forensic Chemistry
De Campos EG, Krotulski AJ, De Martinis BS, Luiz Costa J WIRes Forensic Science Synthetic cathinones are a class of novel psychoactive substances, commonly tested in seized materials by forensic chemistry laboratories. These drugs have been found in...