Toxic adulterants are defined as pharmacologically active substances with action on the Central Nervous System (CNS). When added to the various substances present in drug street samples, they increase the user health risks by compound interaction – or intrinsic toxicity.
Since 2016, scientists at the CFSRE have been working on the analysis of seized material from various parts of the country to identify the patterns of toxic adulterants in different states using high resolution mass spectrometry. This work also includes an assessment of toxic adulterants found worldwide through the International Toxic Adulterant Database (ITAD), which was founded by the Colombo Plan to monitor the spread and extent of toxic adulterating substances in the drug supply internationally. The partnership includes 29 participating countries.
The research on toxic adulterants being conducted by the CFSRE includes the development and validation of methods to analyze these substances. The CFSRE has received samples from all across the United States, and therefore is able analyze the trending on toxic adulterants throughout the country. From an international perspective, a database with adulterant findings from laboratory surveys in 29 different countries is being conducted to build the International Toxic Adulterant Database, also known as the ITAD.
The CFSRE is working to develop informative material including training materials and scientific publications to contribute to the scientific community.
Peer reviewed publications
Non peer reviewed publications